Can cannabinoids contribute to cholecystitis – a case of gangrenous acalculous cholecystitis



gangrenous cholecystitis, cannabinoids, vasospasm, illicit drugs, acalculous


Cannabis legalisation continues to grow globally and its effects on the vascular system have been scrutinized.1 Cannabis has become recognised as a contributor to cardiovascular, cerebrovascular and peripheral vascular disease.2,3 This case report highlights the case of a young male patient presenting with atypical symptoms following cannabis use who developed gangrenous cholecystitis (GC) following vasospasm of his cystic artery. We believe that this is the first-ever case, shared with the anticipation of stimulating more research and prompting recognition of vascular events in this group of patients as our knowledge on the effects of cannabis continues to grow.

Author Biographies

M Bhana, University of the Witwatersrand

Division of Surgery, Department of General Surgery, Pholosong Hospital, South Africa

Y Perner, University of the Witwatersrand

Division of Anatomical Pathology, National Health Laboratory Service, Charlotte Maxeke Johannesburg Academic Hospital, South Africa






Case Report