New hope for scar revision with a modified skin culture technique: a case report

Authors

DOI:

https://doi.org/10.36303/SAJS.03601

Keywords:

cultured epidermal autografts, Kleintjes cultured skin, scar revision, cosmetic outcomes, Vancouver scar scale

Abstract

Cultured epidermal autografts (CEA) are seldom used in scar revision despite evidence of favourable outcomes. We report a case using a modified technique, Kleintjes Cultured Skin (KCS), for revision of childhood burn scars on the lower legs. Keratinocytes were enzymatically isolated, seeded onto the dressing, and incubated for two weeks. KCS was applied directly onto the excised scars. Scar appearance, assessed with the Vancouver Scar Scale, improved from 4 preoperatively to 2 at a follow-up of two and six years, with progressive re-pigmentation, softness, and pliability. The biopsy site also healed favourably. This case supports the potential role of KCS in cosmetic scar revision.

Author Biographies

WG Kleintjes, Stellenbosch University

Department of Surgical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa
Western Cape Provincial Adult Tertiary Burns Centre, Tygerberg Hospital, South Africa

TK Prinsloo, Cape Peninsula University of Technology

Department of Emergency Medical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, South Africa

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Published

2026-03-16

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Section

Online Ahead of Print