Turning the tide: combined resection and radiofrequency ablation of synchronous liver metastases in colorectal cancer

Abstract

Colorectal cancer (CRC) frequently metastasises to the liver, where multimodal therapy offers the best survival outcomes. We report a 45-year-old woman with rectosigmoid adenocarcinoma and synchronous liver metastases who showed an excellent response to neoadjuvant chemotherapy, evidenced by tumour marker decline and radiologic regression. She underwent single-stage colorectal and hepatic resection (HR) with intraoperative radiofrequency ablation. Follow-up imaging confirmed complete metabolic remission and nine months of disease-free survival. This case underscores the effectiveness of integrated systemic therapy and parenchymal-sparing hepatic surgery in synchronous colorectal liver metastasis.