The use of intralesional recombinant human epidermal growth factor (rhEGF) in advanced diabetic foot ulcers in South Africa

Authors

  • TG Mothabeng 1 Military Hospital
  • TK Ngcobo 1 Military Hospital
  • N Singh 1 Military Hospital
  • SC Deprés Hospital Militar Central Doctor Carlos J Finlay
  • MA Valdés Center for Genetic Engineering and Biotechnology
  • AD Tuero Iglesias Centre for Research and Development of Medicines
  • AB Minkova Center for Genetic Engineering and Biotechnology
  • JA Buxadó Center for Genetic Engineering and Biotechnology
  • JE Baldomero Center for Genetic Engineering and Biotechnology
  • A del Río Martín Center for Genetic Engineering and Biotechnology
  • VLM González Center for Genetic Engineering and Biotechnology

Abstract

Treatment of complex diabetic foot ulcers (DFU) with intra- and perilesional injection of recombinant human epidermal growth factor (rhEGF) has been safe and effective in clinical trials. Here, we report results on the efficacy and safety of this treatment in South Africa.

Author Biographies

TG Mothabeng, 1 Military Hospital

Surgical Medical Services, 1 Military Hospital, South Africa

TK Ngcobo, 1 Military Hospital

Surgical Medical Services, 1 Military Hospital, South Africa

N Singh, 1 Military Hospital

Surgical Medical Services, 1 Military Hospital, South Africa

SC Deprés, Hospital Militar Central Doctor Carlos J Finlay

Department of Angiology and Vascular Surgery, Hospital Militar Central Doctor Carlos J Finlay, Cuba

MA Valdés, Center for Genetic Engineering and Biotechnology

Center for Genetic Engineering and Biotechnology, Cuba

AD Tuero Iglesias, Centre for Research and Development of Medicines

Laboratory of Bioequivalence, Centre for Research and Development of Medicines (CIDEM), Cuba

AB Minkova, Center for Genetic Engineering and Biotechnology

Center for Genetic Engineering and Biotechnology, Cuba

JA Buxadó, Center for Genetic Engineering and Biotechnology

Center for Genetic Engineering and Biotechnology, Cuba

JE Baldomero, Center for Genetic Engineering and Biotechnology

Center for Genetic Engineering and Biotechnology, Cuba

A del Río Martín, Center for Genetic Engineering and Biotechnology

Center for Genetic Engineering and Biotechnology, Cuba

VLM González, Center for Genetic Engineering and Biotechnology

Center for Genetic Engineering and Biotechnology, Cuba

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Published

2023-06-30

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