Human amniotic membrane accelerates healing in a hard-to-heal diabetic foot ulcer

Abstract

Human amniotic membrane (HAM) is acquired from the human placenta. This advanced regenerative therapy rich in growth  factors, stem cells and cytokines, limits the extent of continuing inflammatory damage, decreases the microbial bioburden, and promotes progression into the proliferative phase of healing.¹ HAM provides a natural cellular scaffold for cellular adhesion facilitating keratinocyte migration to promote reepithelialisation and enable remodelling to accelerate wound healing.¹ High quality studies with good evidence specify the safe and effective use of HAM in the management of diabetic foot ulcers.²,³