Adrenocortical carcinoma in a patient presenting with recurrent pulmonary emboli

Abstract

Adrenocortical carcinomas are rare malignancies with a clinically heterogeneous presentation. These tumours can be detected incidentally on imaging, where biochemical evaluation is required to assess tumour functionality. This case describes a patient presenting with recurrent pulmonary emboli and an incidental finding of an adrenal mass. Biochemistry revealed hypercortisolism, plus elevated androgen and oestrogen levels despite only mild clinical features of hypercortisolism. Histology confirmed a high-grade adrenocortical carcinoma.